ProMIS Neurosciences (Nasdaq:PMN)
ProMIS is a clinical-stage biotechnology company committed to the discovery and development of therapeutic antibodies selective for toxic oligomers associated with the development and progression of neurodegenerative and other misfolded protein diseases. The Company’s proprietary target discovery engine, EpiSelect™, has been shown to predict novel targets known as Disease Specific Epitopes (DSEs) on the molecular surface of misfolded proteins that cause neurodegenerative and other misfolded protein diseases. PMN310, the Company’s lead product candidate for the treatment of Alzheimer's disease, is a humanized monoclonal antibody that has been designed to selectively target only the toxic oligomers, avoiding plaque, thereby potentially reducing, or eliminating amyloid-related imaging abnormalities (ARIA) liability. In addition, PMN310 could potentially offer an improved efficacy profile over other amyloid-directed therapeutics. PMN310 was granted Fast Track designation by the FDA.
What is your next catalyst (value inflection) update?
Landmark Phase 1b Alzheimer's disease study results from PRECISE-AD. Blinded 6-month top-line data expected mid-2026; 12-month top-line data expected toward end of 2026
Year Founded
2015
Lead Product in Development
PMN310
Development Phase of Lead Product
Phase I
Number of Unlicensed Products Looking for Licensing
In addition to PMN310, the company has two other priority programs and a proprietary antibody drug discovery engine targeting diseases with misfolded proteins
Exchange
Nasdaq
Ticker
PMN
CEO/Top Company Official
Neil Warma

