As biotech companies compete for talent, capital, and speed to value, geographic strategy has become a source of competitive advantage. South Florida has experienced an influx of seasoned operators, rapid expansion of research capabilities across multiple universities, and increasing engagement from both traditional and alternative capital providers. This discussion will examine what is drawing companies and leaders to the region — including operational efficiency, talent arbitrage, access to family office and international capital, and a more coordinated academic ecosystem. Can these factors translate into a durable competitive edge outside legacy hubs — and what must align to convert momentum into a true ecosystem flywheel?